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Generation of single-copy transgenic mouse embryos directly from ES cells by tetraploid embryo complementation
BACKGROUND: Transgenic mice have been used extensively to analyze gene function. Unfortunately, traditional transgenic procedures have only limited use in analyzing alleles that cause lethality because lines of founder mice cannot be established. This is frustrating given that such alleles often rev...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC64498/ https://www.ncbi.nlm.nih.gov/pubmed/11782291 http://dx.doi.org/10.1186/1472-6750-1-12 |