Boolean network modeling of β-cell apoptosis and insulin resistance in type 2 diabetes mellitus

BACKGROUND: Major alteration in lifestyle of human population has promoted Type 2 diabetes mellitus (T2DM) to the level of an epidemic. This metabolic disorder is characterized by insulin resistance and pancreatic β-cell dysfunction and apoptosis, triggered by endoplasmic reticulum (ER) stress, oxid...

Descripción completa

Detalles Bibliográficos
Autores principales: Dutta, Pritha, Ma, Lichun, Ali, Yusuf, Sloot, Peter M.A., Zheng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449890/
https://www.ncbi.nlm.nih.gov/pubmed/30953496
http://dx.doi.org/10.1186/s12918-019-0692-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449890/
https://www.ncbi.nlm.nih.gov/pubmed/30953496
http://dx.doi.org/10.1186/s12918-019-0692-0

Ejemplares similares