Cargando…
Boolean network modeling of β-cell apoptosis and insulin resistance in type 2 diabetes mellitus
BACKGROUND: Major alteration in lifestyle of human population has promoted Type 2 diabetes mellitus (T2DM) to the level of an epidemic. This metabolic disorder is characterized by insulin resistance and pancreatic β-cell dysfunction and apoptosis, triggered by endoplasmic reticulum (ER) stress, oxid...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449890/ https://www.ncbi.nlm.nih.gov/pubmed/30953496 http://dx.doi.org/10.1186/s12918-019-0692-0 |