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Fusing gene expressions and transitive protein-protein interactions for inference of gene regulatory networks
BACKGROUND: Systematic fusion of multiple data sources for Gene Regulatory Networks (GRN) inference remains a key challenge in systems biology. We incorporate information from protein-protein interaction networks (PPIN) into the process of GRN inference from gene expression (GE) data. However, exist...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449891/ https://www.ncbi.nlm.nih.gov/pubmed/30953534 http://dx.doi.org/10.1186/s12918-019-0695-x |