Fusing gene expressions and transitive protein-protein interactions for inference of gene regulatory networks

BACKGROUND: Systematic fusion of multiple data sources for Gene Regulatory Networks (GRN) inference remains a key challenge in systems biology. We incorporate information from protein-protein interaction networks (PPIN) into the process of GRN inference from gene expression (GE) data. However, exist...

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Detalles Bibliográficos
Autores principales: Liu, Wenting, Rajapakse, Jagath C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449891/
https://www.ncbi.nlm.nih.gov/pubmed/30953534
http://dx.doi.org/10.1186/s12918-019-0695-x

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