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Promoting therapeutic angiogenesis of focal cerebral ischemia using thrombospondin-4 (TSP4) gene-modified bone marrow stromal cells (BMSCs) in a rat model

BACKGROUND: A stroke caused by angiostenosis always has a poor prognosis. Bone marrow stromal cells (BMSC) are widely applied in vascular regeneration. Recently, thrombospondin-4 (TSP4) was reported to promote the regeneration of blood vessels and enhance the function of endothelial cells in angioge...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Zhou, Meiling, Wu, Xiangfeng, Li, Zhu, Liu, Bing, Gao, Wenbin, Yue, Jin, Liu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449913/
https://www.ncbi.nlm.nih.gov/pubmed/30947736
http://dx.doi.org/10.1186/s12967-019-1845-z