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A positive feed-forward loop between LncRNA-URRCC and EGFL7/P-AKT/FOXO3 signaling promotes proliferation and metastasis of clear cell renal cell carcinoma

BACKGROUND: The aberrant expression of long noncoding RNAs (lncRNAs) has recently emerged as key molecules in human cancers; however, whether lncRNAs are implicated in the progression of clear cell renal cell carcinoma (ccRCC) remains unclear. METHODS: Candidate lncRNAs were selected using microarra...

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Detalles Bibliográficos
Autores principales: Zhai, Wei, Zhu, Rujian, Ma, Junjie, Gong, Dongkui, Zhang, Haimin, Zhang, Jin, Chen, Yonghui, Huang, Yiran, Zheng, Junhua, Xue, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449923/
https://www.ncbi.nlm.nih.gov/pubmed/30953521
http://dx.doi.org/10.1186/s12943-019-0998-y