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CircDLST promotes the tumorigenesis and metastasis of gastric cancer by sponging miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling

BACKGROUND: Accumulating evidence shows that, the dysregulation of circular RNAs (circRNAs) is associated with the progression of multiple malignancies. But, the underlying mechanisms by which has_circ_0032627 (circDLST) contributed to gastric cancer (GC) remain undocumented. METHODS: The expression...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Hou, Lidan, Liang, Rui, Chen, Xiaoyu, Zhang, Rui, Chen, Wei, Zhu, Jinshui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449953/
https://www.ncbi.nlm.nih.gov/pubmed/30953514
http://dx.doi.org/10.1186/s12943-019-1015-1