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Overexpression of activated CaMKII in the CA1 hippocampus impairs context discrimination, but not contextual conditioning
Calcium/Calmodulin-dependent protein kinase II (CaMKII) plays a key role in the molecular mechanism of memory formation. CaMKII is known to be activated specifically in the activated spines during memory formation. However, it is unclear whether the specific activation of CaMKII is necessary for enc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449978/ https://www.ncbi.nlm.nih.gov/pubmed/30953515 http://dx.doi.org/10.1186/s13041-019-0454-3 |