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Overexpression of activated CaMKII in the CA1 hippocampus impairs context discrimination, but not contextual conditioning

Calcium/Calmodulin-dependent protein kinase II (CaMKII) plays a key role in the molecular mechanism of memory formation. CaMKII is known to be activated specifically in the activated spines during memory formation. However, it is unclear whether the specific activation of CaMKII is necessary for enc...

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Detalles Bibliográficos
Autores principales: Ye, Sanghyun, Kim, Ji-il, Kim, Jooyoung, Kaang, Bong-Kiun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449978/
https://www.ncbi.nlm.nih.gov/pubmed/30953515
http://dx.doi.org/10.1186/s13041-019-0454-3