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Spontaneous C-cleavage of a truncated intein as fusion tag to produce tag-free VP1 inclusion body nanoparticle vaccine against CVB3-induced viral myocarditis by the oral route

BACKGROUND: Oral vaccine is highly desired for infectious disease which is caused by pathogens infection through the mucosal surface. The design of suitable vaccine delivery system is ongoing for the antigen protection from the harsh gastric environment and target to the Peyer’s patches to induce su...

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Detalles Bibliográficos
Autores principales: Qi, Xingmei, Lu, Qian, Hu, JingPing, Xiong, Sidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449988/
https://www.ncbi.nlm.nih.gov/pubmed/30947747
http://dx.doi.org/10.1186/s12934-019-1115-z