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Exploiting microglial and peripheral immune cell crosstalk to treat Alzheimer’s disease
Neuroinflammation is considered one of the cardinal features of Alzheimer’s disease (AD). Neuritic plaques composed of amyloid β and neurofibrillary tangle-laden neurons are surrounded by reactive astrocytes and microglia. Exposure of microglia, the resident myeloid cell of the CNS, to amyloid β cau...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449993/ https://www.ncbi.nlm.nih.gov/pubmed/30953557 http://dx.doi.org/10.1186/s12974-019-1453-0 |