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Exploiting microglial and peripheral immune cell crosstalk to treat Alzheimer’s disease

Neuroinflammation is considered one of the cardinal features of Alzheimer’s disease (AD). Neuritic plaques composed of amyloid β and neurofibrillary tangle-laden neurons are surrounded by reactive astrocytes and microglia. Exposure of microglia, the resident myeloid cell of the CNS, to amyloid β cau...

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Detalles Bibliográficos
Autores principales: Dionisio-Santos, Dawling A., Olschowka, John A., O’Banion, M. Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449993/
https://www.ncbi.nlm.nih.gov/pubmed/30953557
http://dx.doi.org/10.1186/s12974-019-1453-0