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Anti-CNTN1 IgG3 induces acute conduction block and motor deficits in a passive transfer rat model
BACKGROUND: Autoantibodies against the paranodal protein contactin-1 have recently been described in patients with severe acute-onset autoimmune neuropathies and mainly belong to the IgG4 subclass that does not activate complement. IgG3 anti-contactin-1 autoantibodies are rare, but have been detecte...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450014/ https://www.ncbi.nlm.nih.gov/pubmed/30953561 http://dx.doi.org/10.1186/s12974-019-1462-z |