Engineered variants provide new insight into the structural properties important for activity of the highly dynamic, trimeric protein disulfide isomerase ScsC from Proteus mirabilis

Suppressor of copper sensitivity protein C from Proteus mirabilis (PmScsC) is a homotrimeric disulfide isomerase that plays a role in copper tolerance, which is a key virulence trait of this uropathogen. Each protomer of the enzyme has an N-terminal trimerization stem (59 residues) containing a flex...

Descripción completa

Detalles Bibliográficos
Autores principales: Furlong, Emily J., Kurth, Fabian, Premkumar, Lakshmanane, Whitten, Andrew E., Martin, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2019
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450059/
https://www.ncbi.nlm.nih.gov/pubmed/30950400
http://dx.doi.org/10.1107/S2059798319000081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450059/
https://www.ncbi.nlm.nih.gov/pubmed/30950400
http://dx.doi.org/10.1107/S2059798319000081

Ejemplares similares