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Assessing the Protective Potential of H1N1 Influenza Virus Hemagglutinin Head and Stalk Antibodies in Humans

Seasonal influenza viruses are a major cause of human disease worldwide. Most neutralizing antibodies (Abs) elicited by influenza viruses target the head domain of the hemagglutinin (HA) protein. Anti-HA head Abs can be highly potent, but they have limited breadth since the HA head is variable. Ther...

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Detalles Bibliográficos
Autores principales: Christensen, Shannon R., Toulmin, Sushila A., Griesman, Trevor, Lamerato, Lois E., Petrie, Joshua G., Martin, Emily T., Monto, Arnold S., Hensley, Scott E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450120/
https://www.ncbi.nlm.nih.gov/pubmed/30700610
http://dx.doi.org/10.1128/JVI.02134-18