Cargando…
Assessing the Protective Potential of H1N1 Influenza Virus Hemagglutinin Head and Stalk Antibodies in Humans
Seasonal influenza viruses are a major cause of human disease worldwide. Most neutralizing antibodies (Abs) elicited by influenza viruses target the head domain of the hemagglutinin (HA) protein. Anti-HA head Abs can be highly potent, but they have limited breadth since the HA head is variable. Ther...
Autores principales: | Christensen, Shannon R., Toulmin, Sushila A., Griesman, Trevor, Lamerato, Lois E., Petrie, Joshua G., Martin, Emily T., Monto, Arnold S., Hensley, Scott E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450120/ https://www.ncbi.nlm.nih.gov/pubmed/30700610 http://dx.doi.org/10.1128/JVI.02134-18 |
Ejemplares similares
-
Hemagglutinin and Neuraminidase Antibodies Are Induced in an Age- and Subtype-Dependent Manner after Influenza Virus Infection
por: Wong, Sook-San, et al.
Publicado: (2020) -
Glycosylation of the Hemagglutinin Protein of H5N1 Influenza Virus Increases Its Virulence in Mice by Exacerbating the Host Immune Response
por: Zhao, Dongming, et al.
Publicado: (2017) -
A Single-Amino-Acid Substitution at Position 225 in Hemagglutinin Alters the Transmissibility of Eurasian Avian-Like H1N1 Swine Influenza Virus in Guinea Pigs
por: Wang, Zeng, et al.
Publicado: (2017) -
The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases
por: Kühn, Nora, et al.
Publicado: (2016) -
Immune Escape Variants of H9N2 Influenza Viruses Containing Deletions at the Hemagglutinin Receptor Binding Site Retain Fitness In Vivo and Display Enhanced Zoonotic Characteristics
por: Peacock, Thomas P., et al.
Publicado: (2017)