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A designer self-assembled supramolecule amplifies macrophage immune responses against aggressive cancer

Effectively activating macrophages that can ‘eat’ cancer cells is challenging. In particular, cancer cells secrete macrophage colony stimulating factor (MCSF), which polarizes tumour-associated macrophages from an antitumour M1 phenotype to a pro-tumourigenic M2 phenotype. Also, cancer cells can exp...

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Detalles Bibliográficos
Autores principales: Kulkarni, Ashish, Chandrasekar, Vineethkrishna, Natarajan, Siva Kumar, Ramesh, Anujan, Pandey, Prithviraj, Nirgud, Jayashree, Bhatnagar, Harshangda, Ashok, Driti, Ajay, Amrendra Kumar, Sengupta, Shiladitya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450396/
https://www.ncbi.nlm.nih.gov/pubmed/30956894
http://dx.doi.org/10.1038/s41551-018-0254-6