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Regulation of breast tumorigenesis through acid sensors

The low extracellular pH in the microenvironment has been shown to promote tumor growth and metastasis, however, the underlying mechanism is poorly understood. Particularly, little is known how the tumor cell senses the acidic signal to activate the acidosis-mediated signaling. In this study, we sho...

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Detalles Bibliográficos
Autores principales: Gupta, Subash C., Singh, Ramesh, Asters, Mathew, Liu, Jianghua, Zhang, Xu, Pabbidi, Mallikarjuna R., Watabe, Kounosuke, Mo, Yin-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450404/
https://www.ncbi.nlm.nih.gov/pubmed/26686084
http://dx.doi.org/10.1038/onc.2015.477