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Allicin disrupts cardiac Cav1.2 channels via trafficking

Context: Allicin is a potential antiarrhythmic agent. The antiarrhythmic properties of allicin rely on its blockade of various cardiac ion channels. The l-type calcium (Cav1.2) channel provides a pivotal substrate for cardiac electrophysiologic activities. The mechanism of allicin on Cav1.2 remains...

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Detalles Bibliográficos
Autores principales: Han, Dan, Xu, Lingping, Liu, Peng, Liu, Yingying, Sun, Chaofeng, Yin, Yanrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450490/
https://www.ncbi.nlm.nih.gov/pubmed/30929547
http://dx.doi.org/10.1080/13880209.2019.1577469