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Doxorubicin-loaded red blood cells reduced cardiac toxicity and preserved anticancer activity

Doxorubicin (DOX) is one of the most widely used anticancer agents. DOX is known for inducing cardiotoxicity, resulting in the long-term development of heart failure. Intravascular delivery of DOX may benefit from the carriage by red blood cells (RBCs), as they can limit the systemic toxicity while...

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Detalles Bibliográficos
Autores principales: Lucas, Alfredo, Lam, Dawn, Cabrales, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450495/
https://www.ncbi.nlm.nih.gov/pubmed/30929538
http://dx.doi.org/10.1080/10717544.2019.1591544