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A 3D CFD model of the interstitial fluid pressure and drug distribution in heterogeneous tumor nodules during intraperitoneal chemotherapy

Although intraperitoneal chemotherapy (IPC) has evolved into an established treatment modality for patients with peritoneal metastasis (PM), drug penetration into tumor nodules remains limited. Drug transport during IPC is a complex process that depends on a large number of different parameters (e.g...

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Detalles Bibliográficos
Autores principales: Steuperaert, Margo, Debbaut, Charlotte, Carlier, Charlotte, De Wever, Olivier, Descamps, Benedicte, Vanhove, Christian, Ceelen, Wim, Segers, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450529/
https://www.ncbi.nlm.nih.gov/pubmed/30929523
http://dx.doi.org/10.1080/10717544.2019.1588423