Cargando…
A 3D CFD model of the interstitial fluid pressure and drug distribution in heterogeneous tumor nodules during intraperitoneal chemotherapy
Although intraperitoneal chemotherapy (IPC) has evolved into an established treatment modality for patients with peritoneal metastasis (PM), drug penetration into tumor nodules remains limited. Drug transport during IPC is a complex process that depends on a large number of different parameters (e.g...
Autores principales: | Steuperaert, Margo, Debbaut, Charlotte, Carlier, Charlotte, De Wever, Olivier, Descamps, Benedicte, Vanhove, Christian, Ceelen, Wim, Segers, Patrick |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450529/ https://www.ncbi.nlm.nih.gov/pubmed/30929523 http://dx.doi.org/10.1080/10717544.2019.1588423 |
Ejemplares similares
-
Mathematical modeling of intraperitoneal drug delivery: simulation of drug distribution in a single tumor nodule
por: Steuperaert, Margo, et al.
Publicado: (2017) -
Optimization of intraperitoneal aerosolized drug delivery using computational fluid dynamics (CFD) modeling
por: Rahimi-Gorji, Mohammad, et al.
Publicado: (2022) -
Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model
por: Gremonprez, Félix, et al.
Publicado: (2015) -
Data on in vivo selection of SK-OV-3 Luc ovarian cancer cells and intraperitoneal tumor formation with low inoculation numbers
por: De Vlieghere, Elly, et al.
Publicado: (2016) -
Improved xenograft efficiency of esophageal adenocarcinoma cell lines through in vivo selection
por: Melsens, Elodie, et al.
Publicado: (2017)