Polygenic Risk Score Is Associated With Intraocular Pressure and Improves Glaucoma Prediction in the UK Biobank Cohort

PURPOSE: Elevated intraocular pressure (IOP) is an important risk factor for glaucoma. We constructed polygenic risk scores (PRSs) for IOP using the UK Biobank (UKB) data set to test whether the PRSs are associated with IOP and whether using them improves glaucoma prediction. METHODS: We conducted t...

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Detalles Bibliográficos
Autores principales: Gao, X. Raymond, Huang, Hua, Kim, Heejin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450641/
https://www.ncbi.nlm.nih.gov/pubmed/30972231
http://dx.doi.org/10.1167/tvst.8.2.10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450641/
https://www.ncbi.nlm.nih.gov/pubmed/30972231
http://dx.doi.org/10.1167/tvst.8.2.10

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