The mRNA export adaptor Yra1 contributes to DNA double-strand break repair through its C-box domain

Yra1 is an mRNA export adaptor involved in mRNA biogenesis and export in S. cerevisiae. Yra1 overexpression was recently shown to promote accumulation of DNA:RNA hybrids favoring DNA double strand breaks (DSB), cell senescence and telomere shortening, via an unknown mechanism. Yra1 was also identifi...

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Detalles Bibliográficos
Autores principales: Infantino, Valentina, Tutucci, Evelina, Yeh Martin, Noël, Zihlmann, Audrey, Garcia-Molinero, Varinia, Silvano, Géraldine, Palancade, Benoit, Stutz, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450643/
https://www.ncbi.nlm.nih.gov/pubmed/30951522
http://dx.doi.org/10.1371/journal.pone.0206336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450643/
https://www.ncbi.nlm.nih.gov/pubmed/30951522
http://dx.doi.org/10.1371/journal.pone.0206336

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