The Notch signaling pathway controls CD8(+) T cell differentiation independently of the classical effector HES1

During CD8(+) T cell response, Notch signaling controls short-lived-effector-cell (SLEC) generation, but the exact mechanisms by which it does so remains unclear. The Notch signaling pathway can act as a key regulator of Akt signaling via direct transcriptional induction of Hes1, which will then rep...

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Detalles Bibliográficos
Autores principales: De Sousa, Dave Maurice, Duval, Frédéric, Daudelin, Jean-François, Boulet, Salix, Labrecque, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450647/
https://www.ncbi.nlm.nih.gov/pubmed/30951556
http://dx.doi.org/10.1371/journal.pone.0215012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450647/
https://www.ncbi.nlm.nih.gov/pubmed/30951556
http://dx.doi.org/10.1371/journal.pone.0215012

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