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The Notch signaling pathway controls CD8(+) T cell differentiation independently of the classical effector HES1
During CD8(+) T cell response, Notch signaling controls short-lived-effector-cell (SLEC) generation, but the exact mechanisms by which it does so remains unclear. The Notch signaling pathway can act as a key regulator of Akt signaling via direct transcriptional induction of Hes1, which will then rep...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450647/ https://www.ncbi.nlm.nih.gov/pubmed/30951556 http://dx.doi.org/10.1371/journal.pone.0215012 |