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Cell type-dependent function of LATS1/2 in cancer cell growth

The Hippo pathway controls organ size and tissue homeostasis, and its dysregulation often contributes to tumorigenesis. Extensive studies have shown that the Hippo pathway inhibits cell proliferation, and survival in a cell-autonomous manner. We examined the function of the Hippo pathway kinases LAT...

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Detalles Bibliográficos
Autores principales: Pan, Wei-Wei, Moroishi, Toshiro, Koo, Ja Hyun, Guan, Kun-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450751/
https://www.ncbi.nlm.nih.gov/pubmed/30531839
http://dx.doi.org/10.1038/s41388-018-0610-8