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Cell type-dependent function of LATS1/2 in cancer cell growth
The Hippo pathway controls organ size and tissue homeostasis, and its dysregulation often contributes to tumorigenesis. Extensive studies have shown that the Hippo pathway inhibits cell proliferation, and survival in a cell-autonomous manner. We examined the function of the Hippo pathway kinases LAT...
Autores principales: | Pan, Wei-Wei, Moroishi, Toshiro, Koo, Ja Hyun, Guan, Kun-Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450751/ https://www.ncbi.nlm.nih.gov/pubmed/30531839 http://dx.doi.org/10.1038/s41388-018-0610-8 |
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