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Clustering of integrin β cytoplasmic domains triggers nascent adhesion formation and reveals a protozoan origin of the integrin-talin interaction

Integrins and integrin-dependent cell-matrix adhesions are essential for a number of physiological processes. Integrin function is tightly regulated via binding of cytoplasmic proteins to integrin intracellular domains. Yet, the complexity of cell-matrix adhesions in mammals, with more than 150 core...

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Detalles Bibliográficos
Autores principales: Baade, Timo, Paone, Christoph, Baldrich, Adrian, Hauck, Christof R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450878/
https://www.ncbi.nlm.nih.gov/pubmed/30952878
http://dx.doi.org/10.1038/s41598-019-42002-6