O-GlcNAc Transferase Inhibition Differentially Affects Breast Cancer Subtypes

Post-translational modification of intracellular proteins with a single N-acetylglucosamine sugar (O-GlcNAcylation) regulates signaling, proliferation, metabolism and protein stability. In breast cancer, expression of the enzyme that catalyzes O-GlcNAcylation – O-GlcNAc-transferase (OGT), and the ex...

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Detalles Bibliográficos
Autores principales: Barkovskaya, Anna, Seip, Kotryna, Hilmarsdottir, Bylgja, Maelandsmo, Gunhild M., Moestue, Siver A., Itkonen, Harri M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450885/
https://www.ncbi.nlm.nih.gov/pubmed/30952976
http://dx.doi.org/10.1038/s41598-019-42153-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450885/
https://www.ncbi.nlm.nih.gov/pubmed/30952976
http://dx.doi.org/10.1038/s41598-019-42153-6

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