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O-GlcNAc Transferase Inhibition Differentially Affects Breast Cancer Subtypes
Post-translational modification of intracellular proteins with a single N-acetylglucosamine sugar (O-GlcNAcylation) regulates signaling, proliferation, metabolism and protein stability. In breast cancer, expression of the enzyme that catalyzes O-GlcNAcylation – O-GlcNAc-transferase (OGT), and the ex...
Autores principales: | Barkovskaya, Anna, Seip, Kotryna, Hilmarsdottir, Bylgja, Maelandsmo, Gunhild M., Moestue, Siver A., Itkonen, Harri M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450885/ https://www.ncbi.nlm.nih.gov/pubmed/30952976 http://dx.doi.org/10.1038/s41598-019-42153-6 |
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