Metabolic resistance of the D-peptide RD2 developed for direct elimination of amyloid-β oligomers

Alzheimer’s disease (AD) is a neurodegenerative disorder leading to dementia. Aggregation of the amyloid-β peptide (Aβ) plays an important role in the disease, with Aβ oligomers representing the most toxic species. Previously, we have developed the Aβ oligomer eliminating therapeutic compound RD2 co...

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Detalles Bibliográficos
Autores principales: Elfgen, Anne, Hupert, Michelle, Bochinsky, Kevin, Tusche, Markus, González de San Román Martin, Estibaliz, Gering, Ian, Sacchi, Silvia, Pollegioni, Loredano, Huesgen, Pitter F., Hartmann, Rudolf, Santiago-Schübel, Beatrix, Kutzsche, Janine, Willbold, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450887/
https://www.ncbi.nlm.nih.gov/pubmed/30952881
http://dx.doi.org/10.1038/s41598-019-41993-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450887/
https://www.ncbi.nlm.nih.gov/pubmed/30952881
http://dx.doi.org/10.1038/s41598-019-41993-6

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