Cargando…

Autophagy regulates lipid metabolism through selective turnover of NCoR1

Selective autophagy ensures the removal of specific soluble proteins, protein aggregates, damaged mitochondria, and invasive bacteria from cells. Defective autophagy has been directly linked to metabolic disorders. However how selective autophagy regulates metabolism remains largely uncharacterized....

Descripción completa

Detalles Bibliográficos
Autores principales: Saito, Tetsuya, Kuma, Akiko, Sugiura, Yuki, Ichimura, Yoshinobu, Obata, Miki, Kitamura, Hiroshi, Okuda, Shujiro, Lee, Hyeon-Cheol, Ikeda, Kazutaka, Kanegae, Yumi, Saito, Izumu, Auwerx, Johan, Motohashi, Hozumi, Suematsu, Makoto, Soga, Tomoyoshi, Yokomizo, Takehiko, Waguri, Satoshi, Mizushima, Noboru, Komatsu, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450892/
https://www.ncbi.nlm.nih.gov/pubmed/30952864
http://dx.doi.org/10.1038/s41467-019-08829-3