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Autophagy regulates lipid metabolism through selective turnover of NCoR1
Selective autophagy ensures the removal of specific soluble proteins, protein aggregates, damaged mitochondria, and invasive bacteria from cells. Defective autophagy has been directly linked to metabolic disorders. However how selective autophagy regulates metabolism remains largely uncharacterized....
Autores principales: | Saito, Tetsuya, Kuma, Akiko, Sugiura, Yuki, Ichimura, Yoshinobu, Obata, Miki, Kitamura, Hiroshi, Okuda, Shujiro, Lee, Hyeon-Cheol, Ikeda, Kazutaka, Kanegae, Yumi, Saito, Izumu, Auwerx, Johan, Motohashi, Hozumi, Suematsu, Makoto, Soga, Tomoyoshi, Yokomizo, Takehiko, Waguri, Satoshi, Mizushima, Noboru, Komatsu, Masaaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450892/ https://www.ncbi.nlm.nih.gov/pubmed/30952864 http://dx.doi.org/10.1038/s41467-019-08829-3 |
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