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Functional neutralization of anti-IFN-γ autoantibody in patients with nontuberculous mycobacteria infection
Interferon (IFN)-γ is crucial for normal immune surveillance and exhibits immunomodulatory, antimicrobial, and anticancer activity. Patients with nontuberculous mycobacteria (NTM) infection commonly express high levels of anti-IFN-γ autoantibodies (autoAbs) and suffer from recurrent infections due t...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450904/ https://www.ncbi.nlm.nih.gov/pubmed/30952894 http://dx.doi.org/10.1038/s41598-019-41952-1 |