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Development of an ex vivo respiratory pediatric model of bronchopulmonary dysplasia for aerosol deposition studies

Ethical restrictions are limitations of in vivo inhalation studies, on humans and animal models. Thus, in vitro or ex vivo anatomical models offer an interesting alternative if limitations are clearly identified and if extrapolation to human is made with caution. This work aimed to develop an ex viv...

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Detalles Bibliográficos
Autores principales: Montigaud, Yoann, Périnel, Sophie, Dubus, Jean-Christophe, Leclerc, Lara, Suau, Marie, Goy, Clémence, Clotagatide, Anthony, Prévôt, Nathalie, Pourchez, Jérémie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450907/
https://www.ncbi.nlm.nih.gov/pubmed/30952897
http://dx.doi.org/10.1038/s41598-019-42103-2