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MicroRNA let-7g acts as tumor suppressor and predictive biomarker for chemoresistance in human epithelial ovarian cancer

Remarkable deregulation of microRNAs has been demonstrated in epithelial ovarian cancer (EOC). In particular, some of the let-7 miRNA family members have been proposed as tumor suppressors. Here, we explored the functional roles of let-7g in EOC. The ectopic overexpression of let-7g in OVCAR3 and HE...

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Detalles Bibliográficos
Autores principales: Biamonte, Flavia, Santamaria, Gianluca, Sacco, Alessandro, Perrone, Francesca Marta, Di Cello, Annalisa, Battaglia, Anna Martina, Salatino, Alessandro, Di Vito, Anna, Aversa, Ilenia, Venturella, Roberta, Zullo, Fulvio, Costanzo, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450929/
https://www.ncbi.nlm.nih.gov/pubmed/30952937
http://dx.doi.org/10.1038/s41598-019-42221-x