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MicroRNA let-7g acts as tumor suppressor and predictive biomarker for chemoresistance in human epithelial ovarian cancer
Remarkable deregulation of microRNAs has been demonstrated in epithelial ovarian cancer (EOC). In particular, some of the let-7 miRNA family members have been proposed as tumor suppressors. Here, we explored the functional roles of let-7g in EOC. The ectopic overexpression of let-7g in OVCAR3 and HE...
Autores principales: | Biamonte, Flavia, Santamaria, Gianluca, Sacco, Alessandro, Perrone, Francesca Marta, Di Cello, Annalisa, Battaglia, Anna Martina, Salatino, Alessandro, Di Vito, Anna, Aversa, Ilenia, Venturella, Roberta, Zullo, Fulvio, Costanzo, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450929/ https://www.ncbi.nlm.nih.gov/pubmed/30952937 http://dx.doi.org/10.1038/s41598-019-42221-x |
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