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Evaluation of [(68)Ga]DO3A-VS-Cys(40)-Exendin-4 as a PET Probe for Imaging Human Transplanted Islets in the Liver

[(68)Ga]DO3A-VS-Cys(40)-Exendin-4, a glucagon-like peptide 1 receptor agonist, was evaluated as a potential PET tracer for the quantitation of human islets transplanted to the liver. The short-lived PET radionuclide (68)Ga, available on a regular basis from a (68)Ge/(68)Ga generator, is an attractiv...

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Detalles Bibliográficos
Autores principales: Li, Junfeng, Rawson, Jeffrey, Chea, Junie, Tang, Wei, Miao, Lynn, Sui, Feng, Li, Lin, Poku, Erasmus, Shively, John E., Kandeel, Fouad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450933/
https://www.ncbi.nlm.nih.gov/pubmed/30952975
http://dx.doi.org/10.1038/s41598-019-42172-3