Di-n-butyl phthalate epigenetically induces reproductive toxicity via the PTEN/AKT pathway

Di-n-butyl phthalate (DBP) is a kind of ubiquitous chemical linked to hormonal disruptions that affects male reproductive system. However, the mechanism of DBP-induced germ cells toxicity remains unclear. Here, we demonstrate that DBP induces reduction of proliferation, increase of apoptosis and DNA...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ran, Xing, Qian-wei, Wu, Xiao-lu, Zhang, Lei, Tang, Min, Tang, Jing-yuan, Wang, Jing-zi, Han, Peng, Wang, Shang-qian, Wang, Wei, Zhang, Wei, Zhou, Guo-ping, Qin, Zhi-qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450951/
https://www.ncbi.nlm.nih.gov/pubmed/30952838
http://dx.doi.org/10.1038/s41419-019-1547-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450951/
https://www.ncbi.nlm.nih.gov/pubmed/30952838
http://dx.doi.org/10.1038/s41419-019-1547-8

Ejemplares similares