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Di-n-butyl phthalate epigenetically induces reproductive toxicity via the PTEN/AKT pathway

Di-n-butyl phthalate (DBP) is a kind of ubiquitous chemical linked to hormonal disruptions that affects male reproductive system. However, the mechanism of DBP-induced germ cells toxicity remains unclear. Here, we demonstrate that DBP induces reduction of proliferation, increase of apoptosis and DNA...

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Detalles Bibliográficos
Autores principales:	Li, Ran, Xing, Qian-wei, Wu, Xiao-lu, Zhang, Lei, Tang, Min, Tang, Jing-yuan, Wang, Jing-zi, Han, Peng, Wang, Shang-qian, Wang, Wei, Zhang, Wei, Zhou, Guo-ping, Qin, Zhi-qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450951/ https://www.ncbi.nlm.nih.gov/pubmed/30952838 http://dx.doi.org/10.1038/s41419-019-1547-8

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