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The human HOXA9 protein uses paralog-specific residues of the homeodomain to interact with TALE-class cofactors
HOX proteins interact with PBX and MEIS cofactors, which belong to the TALE-class of homeodomain (HD)-containing transcription factors. Although the formation of HOX-PBX complexes depends on a unique conserved HOX motif called hexapeptide (HX), the additional presence of MEIS induces a remodeling of...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450960/ https://www.ncbi.nlm.nih.gov/pubmed/30952900 http://dx.doi.org/10.1038/s41598-019-42096-y |