Effect of genotype and age on cerebral [(18)F]FDG uptake varies between transgenic APP(Swe)-PS1(dE9) and Tg2576 mouse models of Alzheimer’s disease

Back-translation of clinical imaging biomarkers of Alzheimer’s disease (AD), such as alterations in cerebral glucose metabolism detected by [(18)F]FDG positron emission tomography (PET), would be valuable for preclinical studies evaluating new disease-modifying drugs for AD. However, previous confou...

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Detalles Bibliográficos
Autores principales: Snellman, Anniina, Takkinen, Jatta S., López-Picón, Francisco R., Eskola, Olli, Solin, Olof, Rinne, Juha O., Haaparanta-Solin, Merja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450965/
https://www.ncbi.nlm.nih.gov/pubmed/30952945
http://dx.doi.org/10.1038/s41598-019-42074-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450965/
https://www.ncbi.nlm.nih.gov/pubmed/30952945
http://dx.doi.org/10.1038/s41598-019-42074-4

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