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B7-H3 promotes aerobic glycolysis and chemoresistance in colorectal cancer cells by regulating HK2
Accumulating evidence suggests that aerobic glycolysis is important for colorectal cancer (CRC) development. However, the underlying mechanisms have yet to be elucidated. B7-H3, an immunoregulatory protein, is broadly overexpressed by multiple tumor types and plays a vital role in tumor progression....
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450969/ https://www.ncbi.nlm.nih.gov/pubmed/30952834 http://dx.doi.org/10.1038/s41419-019-1549-6 |