B7-H3 promotes aerobic glycolysis and chemoresistance in colorectal cancer cells by regulating HK2

Accumulating evidence suggests that aerobic glycolysis is important for colorectal cancer (CRC) development. However, the underlying mechanisms have yet to be elucidated. B7-H3, an immunoregulatory protein, is broadly overexpressed by multiple tumor types and plays a vital role in tumor progression....

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Detalles Bibliográficos
Autores principales: Shi, Tongguo, Ma, Yanchao, Cao, Lei, Zhan, Shenghua, Xu, Yunyun, Fu, Fengqing, Liu, Cuiping, Zhang, Guangbo, Wang, Zhenxin, Wang, Ruoqin, Lu, Huimin, Lu, Binfeng, Chen, Weichang, Zhang, Xueguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450969/
https://www.ncbi.nlm.nih.gov/pubmed/30952834
http://dx.doi.org/10.1038/s41419-019-1549-6

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