The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα

The class 3 phosphoinositide 3-kinase (PI3K) is required for lysosomal degradation by autophagy and vesicular trafficking, assuring nutrient availability. Mitochondrial lipid catabolism is another energy source. Autophagy and mitochondrial metabolism are transcriptionally controlled by nutrient sens...

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Detalles Bibliográficos
Autores principales: Iershov, Anton, Nemazanyy, Ivan, Alkhoury, Chantal, Girard, Muriel, Barth, Esther, Cagnard, Nicolas, Montagner, Alexandra, Chretien, Dominique, Rugarli, Elena I., Guillou, Herve, Pende, Mario, Panasyuk, Ganna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451001/
https://www.ncbi.nlm.nih.gov/pubmed/30952952
http://dx.doi.org/10.1038/s41467-019-09598-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451001/
https://www.ncbi.nlm.nih.gov/pubmed/30952952
http://dx.doi.org/10.1038/s41467-019-09598-9

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