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Eicosanoids in platelets and the effect of their modulation by aspirin in the cardiovascular system (and beyond)

Platelets are important players in thrombosis and haemostasis with their function being modulated by mediators in the blood and the vascular wall. Among these, eicosanoids can both stimulate and inhibit platelet reactivity. Platelet Cyclooxygenase (COX)‐1‐generated Thromboxane (TX)A(2) is the primar...

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Detalles Bibliográficos
Autores principales: Crescente, Marilena, Menke, Laura, Chan, Melissa V, Armstrong, Paul C, Warner, Timothy D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451075/
https://www.ncbi.nlm.nih.gov/pubmed/29512148
http://dx.doi.org/10.1111/bph.14196