NextPBM: a platform to study cell-specific transcription factor binding and cooperativity

High-throughput (HT) in vitro methods for measuring protein-DNA binding have become invaluable for characterizing transcription factor (TF) complexes and modeling gene regulation. However, current methods do not utilize endogenous proteins and, therefore, do not quantify the impact of cell-specific...

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Detalles Bibliográficos
Autores principales: Mohaghegh, Nima, Bray, David, Keenan, Jessica, Penvose, Ashley, Andrilenas, Kellen K, Ramlall, Vijendra, Siggers, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451091/
https://www.ncbi.nlm.nih.gov/pubmed/30657937
http://dx.doi.org/10.1093/nar/gkz020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451091/
https://www.ncbi.nlm.nih.gov/pubmed/30657937
http://dx.doi.org/10.1093/nar/gkz020

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