Conformational changes and catalytic inefficiency associated with Mot1-mediated TBP–DNA dissociation

The TATA-box Binding Protein (TBP) plays a central role in regulating gene expression and is the first step in the process of pre-initiation complex (PIC) formation on promoter DNA. The lifetime of TBP at the promoter site is controlled by several cofactors including the Modifier of transcription 1...

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Detalles Bibliográficos
Autores principales: Heiss, Gregor, Ploetz, Evelyn, Voith von Voithenberg, Lena, Viswanathan, Ramya, Glaser, Samson, Schluesche, Peter, Madhira, Sushi, Meisterernst, Michael, Auble, David T, Lamb, Don C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451094/
https://www.ncbi.nlm.nih.gov/pubmed/30649478
http://dx.doi.org/10.1093/nar/gky1322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451094/
https://www.ncbi.nlm.nih.gov/pubmed/30649478
http://dx.doi.org/10.1093/nar/gky1322

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