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Hidden sequence specificity in loading of single-stranded RNAs onto Drosophila Argonautes
Argonaute proteins play important roles in gene regulation with small RNAs (sRNAs) serving as guides to targets. Argonautes are believed to bind sRNAs in a sequence non-specific manner. However, we recently discovered that Argonautes selectively load endogenous single-stranded (ss) RNAs, suggesting...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451100/ https://www.ncbi.nlm.nih.gov/pubmed/30590701 http://dx.doi.org/10.1093/nar/gky1300 |