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Reconstitution of the human SRP system and quantitative and systematic analysis of its ribosome interactions

Co-translational protein targeting to membranes depends on the regulated interaction of two ribonucleoprotein particles (RNPs): the ribosome and the signal recognition particle (SRP). Human SRP is composed of an SRP RNA and six proteins with the SRP GTPase SRP54 forming the targeting complex with th...

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Detalles Bibliográficos
Autores principales: Wild, Klemens, Juaire, Keven D, Soni, Komal, Shanmuganathan, Vivekanandan, Hendricks, Astrid, Segnitz, Bernd, Beckmann, Roland, Sinning, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451106/
https://www.ncbi.nlm.nih.gov/pubmed/30649417
http://dx.doi.org/10.1093/nar/gky1324